Assay Detail
Functional
CHEMBL5126787
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Cytotoxicity against human A549 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.80 | 8.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5196001 | — | — | 1 | 8.67 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 6.51 |
| CHEMBL5187702 | — | — | 1 | 5.21 |
| CHEMBL539920 | — | — | 1 | - |
| CHEMBL5175907 | — | — | 1 | - |
| CHEMBL5176801 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5196001 | — | IC50 | = | 2.12 | nM | 8.67 |
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 310.0 | nM | 6.51 |
| CHEMBL5187702 | — | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL539920 | — | IC50 | = | 0.0125 | ug.mL-1 | - |
| CHEMBL5175907 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5176801 | — | IC50 | > | 100000.0 | nM | - |