Assay Detail
Functional
CHEMBL5126791
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Cytotoxicity against human QG-56 cells assessed as cell growth inhibition incubated for 4 days by Cell counting kit-8 assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | QG-56 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Renieramycin-type alkaloids from marine-derived organisms: Synthetic chemistry, biological activity and structural modification.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.08 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539920 | — | — | 1 | 9.12 |
| CHEMBL5201475 | — | — | 1 | 8.74 |
| CHEMBL554604 | JORUNNAMYCIN C | — | 1 | 8.55 |
| CHEMBL451147 | RENIERAMYCIN M | — | 1 | 7.96 |
| CHEMBL5182703 | — | — | 1 | 7.77 |
| CHEMBL5172965 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539920 | — | IC50 | = | 0.76 | nM | 9.12 |
| CHEMBL5201475 | — | IC50 | = | 1.8 | nM | 8.74 |
| CHEMBL554604 | JORUNNAMYCIN C | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL451147 | RENIERAMYCIN M | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL5182703 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL5172965 | — | IC50 | = | 448.0 | nM | 6.35 |