Assay Detail
Binding
CHEMBL5126845
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Binding affinity to human adenosine A3A receptor measured by radioligand-based affinity assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Adenosine receptor antagonists: Recent advances and therapeutic perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.30 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2322924 | — | — | 1 | 8.62 |
| CHEMBL4797181 | — | — | 1 | 8.33 |
| CHEMBL2322923 | — | — | 1 | 7.62 |
| CHEMBL3114160 | — | — | 1 | 6.05 |
| CHEMBL5209445 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2322924 | — | Ki | = | 2.4 | nM | 8.62 |
| CHEMBL4797181 | — | Ki | = | 4.63 | nM | 8.33 |
| CHEMBL2322923 | — | Ki | = | 24.0 | nM | 7.62 |
| CHEMBL3114160 | — | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL5209445 | — | Ki | = | 1300.0 | nM | 5.89 |