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Assay Detail

CHEMBL5126961

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiplatelet activity in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 5 mins followed by ADP addition and measured after 5 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Platelet
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

P2Y<sub>12</sub> antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies.
Al-Najjar BO, Saqallah FG, Abbas MA, Al-Hijazeen SZ, Sibai OA.
Eur J Med Chem (2022) 227 : 113924 -113924
PubMed 34731765 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.73 5.73

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL110370 1 5.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL110370 IC50 = 1850.0 nM 5.73