Assay Detail
Binding
CHEMBL5126989
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Binding affinity to human P2Y12 expressed in astrocytoma cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Astrocyte |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
P2Y<sub>12</sub> antagonists: Approved drugs, potential naturally isolated and synthesised compounds, and related in-silico studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.36 | 7.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1672103 | — | — | 1 | 7.60 |
| CHEMBL496820 | — | — | 1 | 7.29 |
| CHEMBL1671994 | — | — | 1 | 7.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1672103 | — | Ki | = | 25.0 | nM | 7.60 |
| CHEMBL496820 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL1671994 | — | Ki | = | 63.0 | nM | 7.20 |