Assay Detail

CHEMBL5127282

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Binding

Inhibition of mTORC1 (unknown origin)

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Molecular design of dual inhibitors of PI3K and potential molecular target of cancer for its treatment: A review.

Wang Y, Tortorella M.
Eur J Med Chem (2022) 228 : 114039 -114039
PubMed 34894440 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	10.40	10.40

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1236962	OMIPALISIB	2.0	1	10.40

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1236962	OMIPALISIB	IC50	=	0.04	nM	10.40