Assay Detail
Binding
CHEMBL5127312
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Inhibition of mouse FXa
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.51 | 8.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4746164 | — | — | 1 | 8.68 |
| CHEMBL5175994 | — | — | 1 | 8.60 |
| CHEMBL5181169 | — | — | 1 | 8.55 |
| CHEMBL20240 | YM-60828 | — | 1 | 8.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4746164 | — | IC50 | = | 2.1 | nM | 8.68 |
| CHEMBL5175994 | — | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL5181169 | — | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL20240 | YM-60828 | IC50 | = | 6.0 | nM | 8.22 |