Assay Detail
Binding
CHEMBL5127347
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MNK2 measured by Caliper-based biochemical assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
MAP kinase-interacting serine/threonine-protein kinase 2 (CHEMBL4204) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Fragment-to-Lead Medicinal Chemistry Publications in 2020.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.39 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4442209 | — | — | 1 | 7.85 |
| CHEMBL4527170 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4442209 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL4527170 | — | IC50 | = | 12000.0 | nM | 4.92 |