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Assay Detail

CHEMBL5127465

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Quercetin derivatives: Drug design, development, and biological activities, a review.
Alizadeh SR, Ebrahimzadeh MA.
Eur J Med Chem (2022) 229 : 114068 -114068
PubMed 34971873 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.72 5.74

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5181679 1 5.74
CHEMBL19032 PENTAMETHYLQUERCETIN 1 5.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5181679 IC50 = 1838.0 nM 5.74
CHEMBL19032 PENTAMETHYLQUERCETIN IC50 = 2042.0 nM 5.69