Assay Detail
Binding
CHEMBL5127645
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Inhibition of KOP (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Analgesic Opioid Ligand Discovery Based on Nonmorphinan Scaffolds Derived from Natural Sources.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.29 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5178409 | — | — | 1 | 6.16 |
| CHEMBL4848517 | — | — | 1 | 5.00 |
| CHEMBL4859858 | — | — | 1 | 5.00 |
| CHEMBL4546925 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5178409 | — | IC50 | = | 691.0 | nM | 6.16 |
| CHEMBL4848517 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4859858 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4546925 | — | IC50 | = | 10000.0 | nM | 5.00 |