Assay Detail
Functional
CHEMBL5127844
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human KARPAS-422 cells expressing EZH2 Y641N mutant incubated for 14 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KARPAS-422 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent strategies targeting Embryonic Ectoderm Development (EED) for cancer therapy: Allosteric inhibitors, PPI inhibitors, and PROTACs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.10 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065484 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065484 | — | IC50 | = | 80.0 | nM | 7.10 |