Assay Detail
Binding
CHEMBL5127904
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Inhibition of MAO-A (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Drug discovery of histone lysine demethylases (KDMs) inhibitors (progress from 2018 to present).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.57 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL257990 | (+)-TRANYLCYPROMINE | — | 1 | 6.57 |
| CHEMBL81 | RALOXIFENE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL257990 | (+)-TRANYLCYPROMINE | IC50 | = | 269.1 | nM | 6.57 |
| CHEMBL81 | RALOXIFENE | IC50 | > | 200000.0 | nM | - |