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Assay Detail

CHEMBL5128121

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human PC3 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PC-3
Confidence 1 — Organism
Curated By Autocuration

Target

PC-3 (CHEMBL390)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances of human dihydroorotate dehydrogenase inhibitors for cancer therapy: Current development and future perspectives.
Zhang L, Zhang J, Wang J, Ren C, Tang P, Ouyang L, Wang Y.
Eur J Med Chem (2022) 232 : 114176 -114176
PubMed 35151222 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL253467 ISOBAVACHALCONE 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL253467 ISOBAVACHALCONE IC50 = 15060.0 nM 4.82