Assay Detail
Binding
CHEMBL5128136
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Notch in human H4 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | H4 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Small molecules targeting γ-secretase and their potential biological applications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL520733 | SEMAGACESTAT | 3.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL520733 | SEMAGACESTAT | IC50 | = | 14.1 | nM | 7.85 |