Assay Detail
Binding
CHEMBL5128356
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Inhibition of baker's yeast alpha-glucosidase using PNPG as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by microplate reader analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.07 | 5.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3617487 | — | — | 1 | 5.10 |
| CHEMBL3617481 | — | — | 1 | 5.10 |
| CHEMBL5202290 | — | — | 1 | 5.10 |
| CHEMBL3617482 | — | — | 1 | 5.10 |
| CHEMBL3617483 | — | — | 1 | 5.10 |
| CHEMBL3617485 | — | — | 1 | 5.10 |
| CHEMBL3617484 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3617487 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3617481 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL5202290 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3617482 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3617483 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3617485 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL3617484 | — | IC50 | = | 12000.0 | nM | 4.92 |