Assay Detail
Binding
CHEMBL5128362
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Inhibition of baker's yeast alpha-glucosidase using PNP-G as substrate preincubated for 10 mins followed by substrate addition and measured after 20 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Saccharomyces cerevisiae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent results from non-basic glycosidase inhibitors: How structural diversity can inform general strategies for improving inhibition potency.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.33 | 4.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95770 | 4-METHOXYCINNAMIC ACID | — | 1 | 4.36 |
| CHEMBL95956 | 4-METHOXY ETHYL CINNAMATE | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95770 | 4-METHOXYCINNAMIC ACID | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL95956 | 4-METHOXY ETHYL CINNAMATE | IC50 | = | 50000.0 | nM | 4.30 |