Assay Detail
Binding
CHEMBL5128399
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant GSK3-beta
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of inhibitors targeting glycogen synthase kinase-3β for human diseases: Strategies to improve selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.12 | 7.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL402435 | WUWEIZISU B | — | 1 | 7.14 |
| CHEMBL513752 | KADSURANIN | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL402435 | WUWEIZISU B | IC50 | = | 73.0 | nM | 7.14 |
| CHEMBL513752 | KADSURANIN | IC50 | = | 81.0 | nM | 7.09 |