Assay Detail
Functional
CHEMBL5128554
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Antimalarial activity against chloroquine sensitive Plasmodium falciparum 3D7 infected in human erythrocyte assessed as inhibition of parasite growth preincubated with compound for 24 hrs followed by hypoxanthine addition and measured after 24 hrs by [3H]-hypoxanthine incorporation based liquid scintillation counter
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Cell Type | Erythrocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spiral molecules with antimalarial activities: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.10 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2387268 | — | — | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2387268 | — | IC50 | = | 0.8 | nM | 9.10 |