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Assay Detail

CHEMBL5128730

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to recombinant human TrkB receptor ECD assessed as dissociation constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

BDNF/NT-3 growth factors receptor (CHEMBL4898)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Recent advances in natural anti-obesity compounds and derivatives based on in vivo evidence: A mini-review.
Chang YH, Hung HY.
Eur J Med Chem (2022) 237 : 114405 -114405
PubMed 35489224 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL75267 7,8-DIHYDROXYFLAVONE 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL75267 7,8-DIHYDROXYFLAVONE Kd = 10.0 nM 8.00