Assay Detail
Binding
CHEMBL5129915
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Inhibition of human SGLT2 expressed in CHO-K1 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO-K1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Sodium-Glucose Cotransporter Inhibitors as Antidiabetic Drugs: Current Development and Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.72 | 8.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270766 | SERGLIFLOZIN A | — | 1 | 8.62 |
| CHEMBL450044 | SERGLIFLOZIN ETABONATE | 2.0 | 1 | 6.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270766 | SERGLIFLOZIN A | Ki | = | 2.39 | nM | 8.62 |
| CHEMBL450044 | SERGLIFLOZIN ETABONATE | Ki | = | 151.0 | nM | 6.82 |