Assay Detail
Binding
CHEMBL5129916
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Inhibition of human SGLT1 expressed in COS-7 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Sodium-Glucose Cotransporter Inhibitors as Antidiabetic Drugs: Current Development and Future Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.78 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3958686 | REMOGLIFLOZIN | -1.0 | 1 | 4.78 |
| CHEMBL2028665 | REMOGLIFLOZIN ETABONATE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3958686 | REMOGLIFLOZIN | IC50 | = | 16600.0 | nM | 4.78 |
| CHEMBL2028665 | REMOGLIFLOZIN ETABONATE | IC50 | > | 100000.0 | nM | - |