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Assay Detail

CHEMBL5131045

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC in Plasmodium falciparum infected in human erythrocytes incubated for 2 hr in presence of sodium [14C]acetate by radiometry assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Plasmodium falciparum
Cell Type Erythrocyte
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Koshidacins A and B, Antiplasmodial Cyclic Tetrapeptides from the Okinawan Fungus <i>Pochonia boninensis</i> FKR-0564.
Watanabe Y, Hachiya K, Ikeda A, Nonaka K, Higo M, Muramatsu R, Noguchi C, Honsho M, Asami Y, Inahashi Y, Hirose T, Matsui H, Sunazuka T, Hanaki H, Ishii T, Teruya T, Hokari R, Ishiyama A, Iwatsuki M.
J Nat Prod (2022) 85 : 2641 -2649
PubMed 36282784 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.15 9.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL430060 APICIDIN 1 9.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL430060 APICIDIN IC50 = 0.7 nM 9.15