Assay Detail
Binding
CHEMBL5131304
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Nav1.7 T1398M-I1399D mutant expressed in CHO cells at -100 mV holding potential by electrophysiology whole cell patch clamp technique
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of Selective Inhibitors of Na<sub>V</sub>1.7 Templated on Saxitoxin as Therapeutics for Pain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.64 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501134 | SAXITOXIN | — | 1 | 8.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501134 | SAXITOXIN | IC50 | = | 2.3 | nM | 8.64 |