Assay Detail
Binding
CHEMBL5131645
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Inhibition of CDK2 (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.51 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103840 | DINACICLIB | 3.0 | 1 | 9.00 |
| CHEMBL23327 | PURVALANOLA | — | 1 | 8.40 |
| CHEMBL428690 | ALVOCIDIB | 3.0 | 1 | 8.00 |
| CHEMBL5209307 | — | — | 1 | 7.51 |
| CHEMBL14762 | SELICICLIB | 2.0 | 1 | 7.00 |
| CHEMBL280074 | OLOMOUCINE | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103840 | DINACICLIB | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL23327 | PURVALANOLA | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL428690 | ALVOCIDIB | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5209307 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL14762 | SELICICLIB | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL280074 | OLOMOUCINE | IC50 | = | 7000.0 | nM | 5.16 |