Assay Detail

CHEMBL5131682

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiviral activity against SARS-CoV-2 in 1 to 24 hrs pretreated cells measured after 48 hrs by immunostaining method

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

SARS-CoV-2 (CHEMBL4303835) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target SARS-CoV-2

CHEMBL4303835

Anchored from Assay target.

Protein identity SARS-CoV-2

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	1 — Organism
Curated By	Autocuration

Target

SARS-CoV-2 (CHEMBL4303835) ↗

Type	ORGANISM
Organism	Severe acute respiratory syndrome coronavirus 2

Publication

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.
J Med Chem (2022) 65 : 893 -921
PubMed 33539089 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.37	8.37

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3989870	BERZOSERTIB	2.0	1	8.37

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3989870	BERZOSERTIB	IC50	=	4.28	nM	8.37