Assay Detail

CHEMBL5131686

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Functional

Antiviral activity against influenza A virus assessed as inhibition of viral replication

ChEMBL ↗

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Target

Influenza A virus (CHEMBL613740) ↗

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Influenza A virus (CHEMBL613740) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Influenza A virus

CHEMBL613740

Anchored from Assay target.

Protein identity Influenza A virus

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Influenza A virus
Confidence	1 — Organism
Curated By	Autocuration

Target

Influenza A virus (CHEMBL613740) ↗

Type	ORGANISM
Organism	Influenza A virus

Publication

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.
J Med Chem (2022) 65 : 893 -921
PubMed 33539089 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	5.75	5.75

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2158685	ABC-294640	2.0	1	5.75

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2158685	ABC-294640	EC50	=	1780.0	nM	5.75