Assay Detail
Functional
CHEMBL5131767
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Antiviral activity against HCV
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepacivirus hominis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 6.18 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2407818 | — | — | 1 | 7.00 |
| CHEMBL1229535 | — | — | 1 | 6.77 |
| CHEMBL283403 | ENVIROXIME | 2.0 | 1 | 6.70 |
| CHEMBL553 | ERLOTINIB | 4.0 | 1 | 6.22 |
| CHEMBL2093753 | — | — | 1 | 6.12 |
| CHEMBL535 | SUNITINIB | 4.0 | 1 | 5.92 |
| CHEMBL3425865 | — | — | 1 | 5.60 |
| CHEMBL1336 | SORAFENIB | 4.0 | 1 | 5.14 |
| CHEMBL3753017 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2407818 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1229535 | — | EC50 | = | 170.0 | nM | 6.77 |
| CHEMBL283403 | ENVIROXIME | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL553 | ERLOTINIB | EC50 | = | 600.0 | nM | 6.22 |
| CHEMBL2093753 | — | EC50 | = | 760.0 | nM | 6.12 |
| CHEMBL535 | SUNITINIB | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3425865 | — | EC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL1336 | SORAFENIB | EC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL3753017 | — | EC50 | > | 5000.0 | nM | - |