Assay Detail
Functional
CHEMBL5131874
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Antiviral activity against DENV
7
Total Activities
7
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Dengue virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.16 | 7.37 |
| IC50 | 3 | 5.64 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4439128 | — | — | 1 | 7.37 |
| CHEMBL1358485 | — | — | 1 | 6.05 |
| CHEMBL495739 | — | — | 1 | 6.02 |
| CHEMBL4642467 | — | — | 1 | 6.00 |
| CHEMBL4556306 | — | — | 1 | 5.82 |
| CHEMBL4172550 | — | — | 1 | 5.46 |
| CHEMBL34704 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4439128 | — | EC50 | = | 43.0 | nM | 7.37 |
| CHEMBL1358485 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL495739 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL4642467 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL4556306 | — | EC50 | = | 1520.0 | nM | 5.82 |
| CHEMBL4172550 | — | EC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL34704 | — | IC50 | = | 14200.0 | nM | 4.85 |