Assay Detail

CHEMBL5131966

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Binding

Inhibition of PDGFR (unknown origin)

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Kinase Inhibitors as Underexplored Antiviral Agents.

García-Cárceles J, Caballero E, Gil C, Martínez A.
J Med Chem (2022) 65 : 935 -954
PubMed 33970631 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.00	7.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1336	SORAFENIB	4.0	1	7.70
CHEMBL78150	TYRPHOSTIN A9	—	1	6.30

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1336	SORAFENIB	IC50	=	20.0	nM	7.70
CHEMBL78150	TYRPHOSTIN A9	IC50	=	500.0	nM	6.30