Assay Detail
Functional
CHEMBL5132067
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human KHYG-1 cells assessed as reduction in cell growth incubated for 72 hrs by Cell titer-blue assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KHYG-1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T-Cell Prolymphocytic Leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.00 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5192865 | — | — | 1 | 6.30 |
| CHEMBL3693786 | CITARINOSTAT | 2.0 | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5192865 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL3693786 | CITARINOSTAT | IC50 | = | 1980.0 | nM | 5.70 |