Assay Detail
Binding
CHEMBL5135486
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]- Mesulergine from human 5-HT2C receptor at 300 nM incubated for 1 hr by microbeta2 beta-counter analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Improving the treatment of Parkinson's disease: Structure-based development of novel 5-HT<sub>2A</sub> receptor antagonists/inverse agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5205903 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5205903 | — | Ki | = | 2.0 | nM | 8.70 |