Assay Detail
Binding
CHEMBL5135696
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bacterial beta-lactamase VIM-1 using nitrocefin as substrate incubated for 10 mins followed by substrate addition measured every 10 seconds for 10 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bacteria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4633785 | XERUBORBACTAM | 1.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4633785 | XERUBORBACTAM | IC50 | = | 14.0 | nM | 7.85 |