Assay Detail
Binding
CHEMBL5135869
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Binding affinity to 5HT1B receptor (unknown origin) assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of Highly Potent Serotonin 5-HT<sub>2</sub> Receptor Agonists Inspired by Heteroyohimbine Natural Products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.07 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5207529 | — | — | 1 | 7.28 |
| CHEMBL5204071 | — | — | 1 | 7.15 |
| CHEMBL5170784 | — | — | 1 | 6.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5207529 | — | Ki | = | 52.1 | nM | 7.28 |
| CHEMBL5204071 | — | Ki | = | 70.8 | nM | 7.15 |
| CHEMBL5170784 | — | Ki | = | 164.0 | nM | 6.79 |