Assay Detail
Functional
CHEMBL5137248
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Antileishmanial activity against Leishmania donovani MHOM/ET/67:LV82 amastigotes infected in BMDM cell measured after 48 hrs by luciferase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Cell Type | BMDM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.40 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | 7.00 |
| CHEMBL3824266 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL3824266 | — | EC50 | = | 1600.0 | nM | 5.80 |