Assay Detail
Binding
CHEMBL5137550
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Binding affinity to Escherichia coli HPPK
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Virtual screening and <i>in vitro</i> validation identifies the first reported inhibitors of <i>Salmonella enterica</i> HPPK.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.16 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4783114 | — | — | 1 | 6.72 |
| CHEMBL1928285 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4783114 | — | Kd | = | 190.0 | nM | 6.72 |
| CHEMBL1928285 | — | Kd | = | 2500.0 | nM | 5.60 |