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Assay Detail

CHEMBL5137559

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Functional
Antiviral activity against MHV-A59 infected in African green monkey Vero cells assessed as inhibition of plaque formation by viral plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Murine hepatitis virus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Murine hepatitis virus (CHEMBL613733)
Type ORGANISM
Organism Murine hepatitis virus

Publication

Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities.
Cannalire R, Cerchia C, Beccari AR, Di Leva FS, Summa V.
J Med Chem (2022) 65 : 2716 -2746
PubMed 33186044 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.57 5.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1230135 1 5.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1230135 EC50 = 2700.0 nM 5.57