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Assay Detail

CHEMBL5137565

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MERS CoV 3CL protease expressed in Escherichia coli BL21-Gold DE3 cells by FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Middle East respiratory syndrome-related coronavirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities.
Cannalire R, Cerchia C, Beccari AR, Di Leva FS, Summa V.
J Med Chem (2022) 65 : 2716 -2746
PubMed 33186044 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5075209 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5075209 IC50 = 580.0 nM 6.24