Assay Detail
Binding
CHEMBL5137652
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Ser 209 phosphorylation of eIF4E (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Eukaryotic translation initiation factor 4E (CHEMBL4848) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Update on the Development of MNK Inhibitors as Therapeutic Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4073443 | TOMIVOSERTIB | 2.0 | 1 | 8.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4073443 | TOMIVOSERTIB | IC50 | = | 1.4 | nM | 8.85 |