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Assay Detail

CHEMBL5137727

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human U-2OS cells assessed as cell viability
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U2OS
Confidence 1 — Organism
Curated By Autocuration

Target

U2OS (CHEMBL615023)
Type CELL-LINE
Organism Homo sapiens

Publication

NO-HDAC dual inhibitors.
Omidkhah N, Ghodsi R.
Eur J Med Chem (2022) 227 : 113934 -113934
PubMed 34700268 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.02 6.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4646139 1 6.33
CHEMBL4639264 1 5.71

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4646139 EC50 = 467.74 nM 6.33
CHEMBL4639264 EC50 = 1949.84 nM 5.71