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Assay Detail

CHEMBL5137963

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to IDO1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Indoleamine 2,3-dioxygenase 1 (CHEMBL4685)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy.
Tang K, Wang B, Yu B, Liu HM.
Eur J Med Chem (2022) 227 : 113967 -113967
PubMed 34752953 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.47 4.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL571209 INDOXIMOD 2.0 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL571209 INDOXIMOD Ki = 34000.0 nM 4.47