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Assay Detail

CHEMBL5138070

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Sclerotinia sclerotiorum
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Sclerotinia sclerotiorum
Confidence 1 — Organism
Curated By Autocuration

Target

Sclerotinia sclerotiorum (CHEMBL613280)
Type ORGANISM
Organism Sclerotinia sclerotiorum

Publication

Natural and synthetic β-carboline as a privileged antifungal scaffolds.
Dai JK, Dan WJ, Wan JB.
Eur J Med Chem (2022) 229 : 114057 -114057
PubMed 34954591 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 9 5.00 6.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1076544 BOSCALID -1.0 1 6.05
CHEMBL5189548 1 5.27
CHEMBL5175386 1 4.92
CHEMBL5182386 1 4.92
CHEMBL5198764 1 4.89
CHEMBL5190875 1 4.81
CHEMBL5178116 1 4.76
CHEMBL5194941 1 4.75
CHEMBL5204211 1 4.65

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1076544 BOSCALID EC50 = 900.0 nM 6.05
CHEMBL5189548 EC50 = 5380.0 nM 5.27
CHEMBL5175386 EC50 = 12000.0 nM 4.92
CHEMBL5182386 EC50 = 11940.0 nM 4.92
CHEMBL5198764 EC50 = 13000.0 nM 4.89
CHEMBL5190875 EC50 = 15500.0 nM 4.81
CHEMBL5178116 EC50 = 17300.0 nM 4.76
CHEMBL5194941 EC50 = 17700.0 nM 4.75
CHEMBL5204211 EC50 = 22400.0 nM 4.65