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Assay Detail

CHEMBL5138240

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Functional
Antiproliferative activity against human MV4-11 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MV4-11
Confidence 1 — Organism
Curated By Autocuration

Target

MV4-11 (CHEMBL613835)
Type CELL-LINE
Organism Homo sapiens

Publication

Fascinating Transformation of SAM-Competitive Protein Methyltransferase Inhibitors from Nucleoside Analogues to Non-Nucleoside Analogues.
Talukdar A, Mukherjee A, Bhattacharya D.
J Med Chem (2022) 65 : 1662 -1684
PubMed 35014841 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.43 4.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4541986 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4541986 IC50 = 37100.0 nM 4.43