Assay Detail
Binding
CHEMBL5138330
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant HDAC1 using fluorogenic substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.40 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109 | VALPROIC ACID | 4.0 | 1 | 4.40 |
| CHEMBL1746 | SODIUM PHENYLBUTYRATE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109 | VALPROIC ACID | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL1746 | SODIUM PHENYLBUTYRATE | IC50 | = | 162000.0 | nM | - |