Assay Detail
Binding
CHEMBL5138446
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Trypanosoma cruzi PTR1 using folic acid as substrate in presence of NADPH by spectrophotometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Trypanosoma cruzi |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 10.42 | 10.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34259 | METHOTREXATE | 4.0 | 1 | 10.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34259 | METHOTREXATE | IC50 | = | 0.038 | nM | 10.42 |