Assay Detail
Binding
CHEMBL5138534
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NF-kappaB (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Nuclear factor NF-kappa-B complex (CHEMBL2094258) ↗| Type | PROTEIN COMPLEX GROUP |
| Organism | Homo sapiens |
Publication
Development of Dual Inhibitors Targeting Epidermal Growth Factor Receptor in Cancer Therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.04 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065300 | — | — | 1 | 6.52 |
| CHEMBL4073912 | — | — | 1 | 6.22 |
| CHEMBL4088718 | — | — | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065300 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL4073912 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL4088718 | — | IC50 | = | 4100.0 | nM | 5.39 |