Assay Detail
Functional
CHEMBL5138617
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against human SBcl2 cells assessed as reduction in cell viability incubated for 72 hrs by XTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SBcl2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.01 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5205851 | — | — | 1 | 6.05 |
| CHEMBL267024 | DIMETHYLACRYLSHIKONIN | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5205851 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL267024 | DIMETHYLACRYLSHIKONIN | IC50 | = | 1100.0 | nM | 5.96 |