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Assay Detail

CHEMBL5138679

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against human HUVEC cells incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Homo sapiens
Cell Type HUVEC
Confidence 1 — Organism
Curated By Autocuration

Target

HUVEC (CHEMBL613979)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances of antitumor shikonin/alkannin derivatives: A comprehensive overview focusing on structural classification, synthetic approaches, and mechanisms of action.
Valipour M.
Eur J Med Chem (2022) 235 : 114314 -114314
PubMed 35367708 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.21 4.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3327385 1 4.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3327385 IC50 = 61900.0 nM 4.21