Assay Detail

CHEMBL5139925

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiviral activity against HCoV-OC43 assessed as viral growth inhibition

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Human coronavirus OC43
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.

Tan H, Hu Y, Jadhav P, Tan B, Wang J.
J Med Chem (2022) 65 : 7561 -7580
PubMed 35620927 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.98	6.98

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL55400	PROFLAVINE	2.0	1	6.98

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL55400	PROFLAVINE	IC50	=	105.0	nM	6.98