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Assay Detail

CHEMBL5140192

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of mouse KLK7 assessed as inhibition constant
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Kallikrein-7 (CHEMBL4295910)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Phage Display Selected Cyclic Peptide Inhibitors of Kallikrein-Related Peptidases 5 and 7 and Their <i>In Vivo</i> Delivery to the Skin.
Gonschorek P, Zorzi A, Maric T, Le Jeune M, Schüttel M, Montagnon M, Gómez-Ojea R, Vollmar DP, Whitfield C, Reymond L, Carle V, Verma H, Schilling O, Hovnanian A, Heinis C.
J Med Chem (2022) 65 : 9735 -9749
PubMed 35653695 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.39 8.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5203652 1 8.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5203652 Ki = 4.1 nM 8.39