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Assay Detail

CHEMBL5140871

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to Pseudomonas aeruginosa LecA assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Pseudomonas aeruginosa
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

PA-I galactophilic lectin (CHEMBL3351196)
Type SINGLE PROTEIN
Organism Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)

Publication

Small Carbohydrate Derivatives as Potent Antibiofilm Agents.
Singh K, Kulkarni SS.
J Med Chem (2022) 65 : 8525 -8549
PubMed 35777073 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.23 4.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL467773 1 4.30
CHEMBL442951 1 4.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL467773 IC50 = 50000.0 nM 4.30
CHEMBL442951 IC50 = 70000.0 nM 4.16